Our team’s efforts will advance understanding of the mechanisms and kinetics of multiphase fluid-formation reaction with rock or coal under GS conditions. The project will focus on (1) identifying parameters controlling GS operation by multiscale investigation of the fate and transport of injected CO2 in GS sites, (2) linking physical property changes (e.g., porosity and permeability) with geochemical reactions, (3) enhancing mineral trapping in carbonate formation by understanding nucleation rates and mechanisms in CO2-water-rock systems, (4) scaling-up from nanoscale observations to macroscale predictions, and (5) delineating the differences and similarities among GS methods. The proposed research will use multiscale and multidisciplinary techniques and state-of-the-art experimental approaches to improve monitoring and modeling techniques of GS and provide more accurate geochemical and geophysical parameters. The findings can be used to maintain the quality of drinking water, public health, and the environment.